Endocrine Abstracts

Introduction: Cryptorchidism is unilateral or bilateral absence of the testes from the scrotum. One of the differential diagnosis is congenital bilateral anorchia. Vanishing testes syndrome is associated with low serum AMH concentrations and an absent or subnormal response to stimulation with hCG. We report the case of a 22-year-old boy diagnosted with bilateral cryptorchidism and hypergonadotropic hypogonadism at the age of 17 years old. At the time of diagnosis the scrotum w...

Introduction: Primary hyperparathyroidism is typically caused by a parathyroid adenoma (80-85% of the cases). Very rare causes are represented by parathyroid carcinoma and atypical parathyroid adenoma (0.5-1.5% of the cases). Atypical parathyroid adenomas have atypical histological features, not sufficient to be considered a carcinoma, and have an uncertain malignant potential and risk of recurrence. We report the case of a 66-year-old man referred from another medical center ...

Background: The rapid advancements in the field of allogenic hematopoietic stem cell transplantation (allo-HSCT) and better management of acute postprocedural complications have led to increased life expectancy, but at the same time to higher incidences of long-term complications. Conditioning regimens (chemotherapy, total body irradiation), immunosuppresive treatments and immune dysregulation threaten endocrine and metabolic functions, leading to late effects, including hypog...

Cushing’s syndrome, whether it is ACTH-dependent or ACTH-independent, causes many complications due to chronic exposure of tissues to a glucocorticoid excess. Some of these are arterial hypertension, obesity, osteoporosis, coagulopathies, impaired glucose tolerance and diabetes. We present a case of Cushing’s syndrome diagnosed in a 64-year-old female that was referred to the Endocrinology Department from the Physical Medicine and Rehabilitation Department due to mul...

Background: Childhood acute lymphoblastic leukemia (ALL) is no longer a death sentence. With survival rates approaching 90%, focus needs to shift towards improving long-term quality of life. Compared to the general population, adult survivors have four-fold excess risk of mortality secondary to cardiovascular diseases. Thus, modifiable risk factors, such as altered glucose metabolism, are of great importance and should be actively sought after. Studies show high prevalences of...